Coagulation and Fibrinolysis in Obstructive Sleep Apnoea
نویسندگان
چکیده
Obstructive sleep apnoea (OSA) is a common disease which characterised by repetitive collapse of the upper airways during resulting in chronic intermittent hypoxaemia and frequent microarousals, consequently leading to sympathetic overflow, enhanced oxidative stress, systemic inflammation, metabolic disturbances. OSA associated with increased risk for cardiovascular morbidity mortality, accelerated coagulation, platelet activation, impaired fibrinolysis serve link between disease. In this article we briefly describe physiological coagulation focusing on processes could be altered OSA. Then, discuss how OSA-associated disturbances, such as hypoxaemia, system affect these processes. Finally, critically review literature OSA-related changes markers fibrinolysis, potential reasons discrepancies, comment clinical implications future research needs.
منابع مشابه
Paediatric obstructive sleep apnoea.
Department of Otolaryngology, James Cook University Hospital, Middlesbrough TS4 3BW Department of Paediatric Otolaryngology, Royal Hospital for Sick Children, Glasgow G3 8SJ Department of Paediatric Respiratory Medicine, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP Department of Anaesthesia, James Cook University Hospital, Middlesbrough TS4 3BW Correspondence to: S Powell steven_m_powe...
متن کاملObstructive sleep apnoea and anaesthesia
Obstructive sleep apnoea (OSA) correlates positively with obesity and age, both of which are becoming increasingly prevalent. Obstructive sleep apnoea occurs much more frequently in clinical practice than formerly diagnosed, and that this condition represents complex challenges for difficulty in mask ventilation, laryngoscopic intubation, accelerated arterial desaturation, postoperative monitor...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2021
ISSN: ['1661-6596', '1422-0067']
DOI: https://doi.org/10.3390/ijms22062834